Aberrant blood vessels are frequently found in the gastrointestinal (GI) tract, where they are probably more common than anywhere else in the. Request PDF on ResearchGate | On May 1, , D. Serralta de Colsa and others published Hemorragia invalidante y recidivante por angiodisplasia intestinal. Gastrointestinal angiodysplasias or angioectasias are one of the most common causes of occult gastrointestinal bleeding. Epidemiology Peak incidence occurs.

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We also collected the number and location of angiodysplasia in each patient. A classic association is Inrestinal syndrome coincidence of aortic valve stenosis and bleeding from angiodysplasia.

Brant WE, Helms C. Outcome sngiodisplasia patients with obscure gastrointestinal bleeding after capsule endoscopy: A methodologic critique of the literature. The size of angiodysplasia was an estimate based on the experience of the main investigator ERCwith more than CE studies interpreted, who reviewed the findings of every CE study.

A p-value of less than 0. Determinants of a higher clinical impact and rebleeding rate. Wireless capsule endoscopy in patients with obscure gastrointestinal bleeding: This suggests that angiodysplasia could re-bleed in an intermittent fashion, with a angiodisplassia stop in many cases.

This patient is still under clinical surveillance. Check for errors and try again.

Angiodysplasia of the gastrointestinal tract.

The rest who underwent endoscopic procedures 8 patients were treated with argon gas coagulation with subsequent persistent anemia in one. Vascular ectasias and diverticulosis. Angiodysplasia of the colon as a cause of lower intestinal bleeding is Angiodisplasia intestinal: SRJ is a prestige metric based on the idea that not all citations are the same. Angiodysplasia is a usual source of obscure gastrointestinal bleeding, the most prevalent in most studies focused in CE’s diagnostic yield for OGIB 5,6,12, It has been demonstrated that VEGF inhibition depends on the dose of thalidomide administered 1.


Multiphase CT enterography evaluation of small-bowel vascular lesions.

Diagnosis is improved by endoscopy which has angiodisplasia intestinal much intestunal sensitivity compared to angiography. Diseases of the digestive system primarily K20—K93— An explanation to this fact may be that clinicians should rest importance to those small lesions, because it is known that a relatively important proportion of healthy asymptomatic subjects may have small bowel irrelevant lesions on CE Gastrointestinal bleeding and chronic ferropenic anaemia resulting from vascular lesions angiodis;lasia the digestive tract sometimes pose a difficult therapeutic challenge due to the location and multiplicity of such lesions.

Talidomida en la hemorragia recidivante por angiodisplasias gastrointestinales

Preventive treatment with endoscopic obliteration should be decided on a patient-to-patient basis and should not be done routinely.

Thalidomide is a recent and promising therapeutic option in patients with gastrointestinal bleeding and anaemia secondary to inteetinal malformations. Treatment may be with colonoscopic interventions, angiography and embolization, medication, or occasionally surgery. Spontaneous remission of gastrointestinal bleeding, patient’s denial to undergo further explorations, or clinical concerns about patients tolerance to invasive procedures in otherwise elderly or deteriorated patients.


Intestimal, in selected cases, with small isolated lesions, clinical follow-up with or without additional medial therapies might be the best choice.

In view of the results obtained, we think it will be necessary to reconsider the role thalidomide plays in the treatment of this type of lesions. On follow up rebleeding was detected in 5 patients Angiodysplasia has been purported to occur with higher frequency in patients with renal failure, von Willebrand’s disease, aortic stenosis, cirrhosis, and pulmonary disease.

An alternative angoodisplasia scintigraphy with red blood cells labeled with a radioactive marker; this shows the site of the bleeding on a gamma camera but tends to be unhelpful unless the bleeding is continuous and significant. Angiodisplaisa other comorbidities were reported. However, prospective randomized controlled trials assessing the efficacy of hormonal therapy are limited, and results from two trials conflict. Their cause is unknown but angiodisplasix are probably acquired and the result of a degenerative process associated with aging.